Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 3/20 | 0.34 |
| ▸ | CA6 | P23280 | 3/20 | 0.34 |
| ▸ | CA5A | P35218 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | F13A1 | P00488 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207371 | 0.93 | TDP1 (0.38) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL7204452 | 0.84 | PAOX (0.42) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL7209803 | 0.84 | PAOX (0.42) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL7204574 | 0.84 | PAOX (0.42) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL7203559 | 0.84 | PAOX (0.42) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL7205258 | 0.84 | PAOX (0.42) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL5928869 | 0.83 | PAOX (0.44) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL8933100 | 0.77 | MAOA (0.41) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL9831022 | 0.77 | PAOX (0.51) | MAOAMAOBPAOXTDP1HDAC6 | |
| SCHEMBL13731881 | 0.76 | DGAT1 (0.39) | MAOAMAOBPAOXTDP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912584-B1 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | HOFFMANN LA ROCHE (CH) | 2002-12-18 | — | — | EP | disclosed |
| EP-0912584-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003519-A9 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | — | 1998-07-16 | — | — | WO | disclosed |
| WO-1998003519-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |