SCHEMBL7207267

SCHEMBL7207267

CCCCCCCCCCc1cc(Cl)ccc1C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 2/20 0.45
FLT1 P17948 1/20 0.45
FLT4 P35916 1/20 0.45
KDR P35968 1/20 0.45
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 3/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
GLA P06280 2/20 0.44
GAA P10253 2/20 0.44
HTT P42858 2/20 0.44
POLB P06746 2/20 0.44
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
SCN5A Q14524 3/20 0.43
SCN9A Q15858 3/20 0.43
CYP3A4 P08684 2/20 0.42
PPARA Q07869 2/20 0.42
NR1I2 O75469 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045482 0.98 SIRT1 (0.46) SIRT1FLT1FLT4KDRKDM4E
SCHEMBL28837661 0.94 FLT1 (0.47) SIRT1FLT1FLT4KDRKDM4E
SCHEMBL28252825 0.87 FLT1 (0.56) SIRT1FLT1FLT4KDRKDM4E
SCHEMBL8922126 0.86 PPARA (0.54) KDM4EALDH1A1MEN1KMT2APPARA
SCHEMBL27609036 0.86 FLT1 (0.46) SIRT1FLT1FLT4KDRKDM4E
SCHEMBL6057107 0.86 PPARA (0.54) KDM4EALDH1A1MEN1KMT2APPARA
SCHEMBL5710049 0.86 PPARA (0.54) KDM4EALDH1A1MEN1KMT2APPARA
SCHEMBL20553924 0.83 MEN1 (0.45) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL29290752 0.83 MEN1 (0.45) KDM4EALDH1A1MEN1MAPTKMT2A
SCHEMBL27804389 0.83 MEN1 (0.45) KDM4EALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6537410-B2 Thermal transfer recording system POLAROID CORPORATION 2003-03-25 US claimed
EP-1263607-A1 THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE POLAROID CORPORATION (US) 2002-12-11 EP claimed
US-20010043239-A1 Thermal transfer recording system MOROOD INTERNATIONAL, SPC (SA) 2001-11-22 US claimed
WO-2001056805-A1 THERMAL TRANSFER RECORDING SYSTEM HAVING AN AMORPHOUS DYE PHASE POLAROID CORPORATION (US) 2001-08-09 WO claimed