Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205536 | 0.89 | TLR7 (0.44) | TLR7ADORA2AADORA1MAPTMAPK1 | |
| SCHEMBL7204601 | 0.86 | ADORA2A (0.60) | TLR7ADORA2AADORA1LMNAMAPT | |
| SCHEMBL5730944 | 0.80 | TLR7 (0.55) | TLR7ADORA2AADORA1MAPK1ALDH1A1 | |
| SCHEMBL7204709 | 0.79 | ADORA2A (0.47) | TLR7ADORA2AADORA1MAPK1ALDH1A1 | |
| SCHEMBL7212493 | 0.79 | ADORA2A (0.47) | TLR7ADORA2AADORA1MAPK1 | |
| SCHEMBL2060321 | 0.78 | ADORA2A (0.46) | TLR7ADORA2AADORA1MAPTMAPK1 | |
| SCHEMBL14944613 | 0.78 | ADORA2A (0.46) | TLR7ADORA2AADORA1MAPK1 | |
| SCHEMBL10174942 | 0.78 | TLR7 (0.49) | TLR7ADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL7209948 | 0.78 | TSHR (0.52) | TLR7ADORA2AADORA1LMNAMAPT | |
| SCHEMBL19370095 | 0.77 | ADORA2A (0.45) | TLR7ADORA2AADORA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |