Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31756877 | 0.90 | NPSR1 (0.53) | TBXAS1SIRT3TDP1NPSR1 | |
| SCHEMBL23563125 | 0.87 | NOTUM (0.43) | TBXAS1SIRT3TDP1 | |
| SCHEMBL2434056 | 0.87 | SIRT3 (0.50) | TBXAS1SIRT3TDP1 | |
| SCHEMBL25046268 | 0.79 | SIRT3 (0.44) | TBXAS1SIRT3TDP1NPSR1 | |
| SCHEMBL3582588 | 0.79 | SIRT3 (0.47) | TBXAS1SIRT3TDP1SMN1; SMN2 | |
| SCHEMBL10788672 | 0.78 | SIRT3 (0.51) | TBXAS1SIRT3TDP1 | |
| SCHEMBL827903 | 0.77 | TDP1 (0.43) | TBXAS1SIRT3TDP1 | |
| SCHEMBL2995694 | 0.77 | AOC1 (0.50) | TBXAS1TDP1HDAC3MAPK1ADRA1A | |
| SCHEMBL30428438 | 0.76 | TBXAS1 (0.44) | TBXAS1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL23599089 | 0.76 | NPSR1 (0.53) | TBXAS1SIRT3TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882712-B1 | PROCESS FOR PREPARING ACID SALTS OF GAMMA-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6197961-B1 | HYDROGENATION OF G-(PYRIDYL)BUTYRIC ACID SALT IN SOLVENT USING PALLADIUM, RHODIUM, OR RUTHENIUM CATALYST; HYDROLYSIS, DECARBOXYLATION | KOEI CHEMICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0882712-A1 | PROCESS FOR PREPARING ACID SALTS OF $g(g)-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |