⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879490 | 0.80 | — | — | |
| SCHEMBL2099259 | 0.76 | — | — | |
| SCHEMBL19897293 | 0.75 | — | — | |
| SCHEMBL514393 | 0.74 | — | — | |
| SCHEMBL29173183 | 0.74 | — | — | |
| SCHEMBL13735517 | 0.74 | — | — | |
| SCHEMBL8888937 | 0.74 | — | — | |
| SCHEMBL28177679 | 0.72 | — | — | |
| SCHEMBL23465208 | 0.72 | CHRNB2 (0.43) | — | |
| SCHEMBL11344389 | 0.72 | ACHE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610738-B2 | Treatment of Alzheimer's Disease by combining both acetylcholinesterase inhibitory activity and antioxidant activity (by virtue of their carbamoyl and flavonoid pharmacophores) | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2003-08-26 | — | — | US | disclosed |
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-09-12 | — | — | US | disclosed |