SCHEMBL7207598

CCCCCCCCCCCC(=O)c1c(C(=O)O)n(CCOc2cccc(CC(=O)O)c2)c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	PLA2G2A	P14555	8/20	0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3680966	0.90	PLA2G2A (0.75)	PLA2G2A
SCHEMBL7208318	0.88	PLA2G2A (0.55)	PLA2G2A
SCHEMBL9267156	0.80	PLA2G2A (0.78)	PLA2G2A
SCHEMBL9263596	0.80	PLA2G2A (0.78)	PLA2G2A
SCHEMBL9264175	0.80	PLA2G2A (0.78)	PLA2G2A
SCHEMBL7212268	0.78	PLA2G2A (0.57)	PLA2G2A
SCHEMBL9268578	0.78	PLA2G2A (0.69)	PLA2G2A
SCHEMBL9270260	0.77	PLA2G2A (0.74)	PLA2G2A
SCHEMBL7207538	0.76	PLA2G2A (0.61)	PLA2G2A
SCHEMBL3683619	0.76	PLA2G2A (0.59)	PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0923546-B1	ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2	MERCKLE GMBH (DE)	2003-11-26	—	—	EP	claimed
US-6310217-B1	ANTIINFLAMMATORY AND ANALGESIC AGENTS	MERCKLE GMBH (DE)	2001-10-30	—	—	US	claimed
EP-0923546-B1	ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2	MERCKLE GMBH (DE)	2003-11-26	—	—	EP	disclosed
US-6310217-B1	ANTIINFLAMMATORY AND ANALGESIC AGENTS	MERCKLE GMBH (DE)	2001-10-30	—	—	US	disclosed