Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 12/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212268 | 0.91 | PLA2G2A (0.57) | PLA2G2A | |
| SCHEMBL7207598 | 0.88 | PLA2G2A (0.71) | PLA2G2A | |
| SCHEMBL9264177 | 0.81 | PLA2G2A (0.58) | PLA2G2ACNR2 | |
| SCHEMBL9267160 | 0.81 | PLA2G2A (0.58) | PLA2G2ACNR2 | |
| SCHEMBL9263602 | 0.81 | PLA2G2A (0.58) | PLA2G2ACNR2 | |
| SCHEMBL9268582 | 0.81 | PLA2G2A (0.53) | PLA2G2A | |
| SCHEMBL9270263 | 0.79 | PLA2G2A (0.54) | PLA2G2A | |
| SCHEMBL7207540 | 0.79 | OXER1 (0.48) | PLA2G2A | |
| SCHEMBL3680966 | 0.78 | PLA2G2A (0.75) | PLA2G2A | |
| SCHEMBL7211985 | 0.77 | PLA2G2A (0.53) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923546-B1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2003-11-26 | — | — | EP | claimed |
| EP-0923546-B1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2003-11-26 | — | — | EP | disclosed |