Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15947627 | 0.88 | NCF1 (0.54) | NCF1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6102087 | 0.84 | NCF1 (0.50) | NCF1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6853883 | 0.81 | NCF1 (0.47) | NCF1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL17370956 | 0.80 | NCF1 (0.43) | NCF1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL15940574 | 0.79 | ADORA2A (0.54) | NCF1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6851753 | 0.78 | NCF1 (0.44) | NCF1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL15947637 | 0.78 | ACACB (0.44) | NCF1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL5233382 | 0.77 | GRM5 (0.51) | NCF1LOXL2MAPTKDM4ECYP1A2 | |
| SCHEMBL15940617 | 0.77 | NCF1 (0.43) | NCF1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1160101 | 0.76 | NCF1 (0.50) | NCF1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | claimed |