Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.72 |
| ▸ | MMP1 | P03956 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GRK2 | P25098 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207765 | 1.00 | MMP13 (0.72) | MMP13MMP1HTTNPSR1KMT2A | |
| SCHEMBL7212088 | 0.84 | MMP13 (1.00) | MMP13MMP1HTTNPSR1KMT2A | |
| SCHEMBL7212082 | 0.84 | MMP13 (1.00) | MMP13MMP1HTTNPSR1KMT2A | |
| SCHEMBL8204581 | 0.81 | MMP13 (0.71) | MMP13MMP1HTTNPSR1KMT2A | |
| SCHEMBL7212058 | 0.81 | MMP13 (0.71) | MMP13MMP1HTTNPSR1KMT2A | |
| SCHEMBL7212062 | 0.81 | MMP13 (0.71) | MMP13MMP1HTTNPSR1KMT2A | |
| SCHEMBL29296550 | 0.78 | MMP13 (0.76) | MMP13MMP1HTTNPSR1KMT2A | |
| SCHEMBL1239560 | 0.76 | F2RL1 (0.53) | KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1236954 | 0.76 | F2RL1 (0.53) | KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7207708 | 0.75 | MMP13 (0.71) | MMP13MMP1HTTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939628-B1 | THIOL SULFONE METALLOPROTEASE INHIBITORS | MONSANTO CO (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6013649-A | BOND DISORDERS; AUTOIMMUNE DISEASES; ANTITUMOR AGENTS | MONSANTO COMPANY (US) | 2000-01-11 | — | — | US | disclosed |