Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274104 | 1.00 | TDP1 (0.52) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL2417683 | 0.90 | TDP1 (0.56) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL28331140 | 0.80 | CA2 (0.52) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL28679723 | 0.80 | ALDH1A1 (0.52) | TDP1CES2CES1LMNAALDH1A1 | |
| SCHEMBL8445181 | 0.80 | CES1 (0.60) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL3948673 | 0.77 | CA12 (0.44) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL10530602 | 0.77 | CA12 (0.44) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL20133901 | 0.77 | KMT2A (0.51) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL11377658 | 0.76 | TDP1 (0.52) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL338162 | 0.76 | TDP1 (0.52) | TDP1L3MBTL1CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4334377-A | — | — | None | — | — | JP | disclosed |
| US-6607710-B1 | Provide a bisphosphonic acid derivative and said bisphosphonic acid derivative being labeled with a radioactive nuclide, which has properties of rapid accumulation to the bone and rapid urinary excretion. | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1092723-A2 | Bisphosphonic acid derivative and compound thereof labelled with radioactive nuclide | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |
| EP-0770063-A1 | TECHNETIUM-SULPHONAMIDE COMPLEXES, THEIR USE, PHARMACEUTICAL AGENTS CONTAINING THEM, AND PROCESS FOR PRODUCING THE COMPLEXES AND AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996002500-A1 | TECHNETIUM-SULPHONAMIDE COMPLEXES, THEIR USE, PHARMACEUTICAL AGENTS CONTAINING THEM, AND PROCESS FOR PRODUCING THE COMPLEXES AND AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |
| WO-1994022816-A1 | METAL CHELATING COMPOUNDS | AMERSHAM INTERNATIONAL PLC (GB) | 1994-10-13 | — | — | WO | disclosed |
| EP-0618191-A1 | Metal chelating compounds | AMERSHAM INTERNATIONAL plc (GB) | 1994-10-05 | — | — | EP | disclosed |
| EP-0495265-B1 | Acid-labile linker molecules | AKZO NOBEL NV (NL) | 1994-08-03 | — | — | EP | disclosed |
| US-5306809-A | Cancer immune therapy | AKZO N.V. (NL) | 1994-04-26 | — | — | US | disclosed |
| JP-H04334377-A | ACID-LABILE LINKER MOLECULE | AKZO NV | 1992-11-20 | — | — | JP | disclosed |
| EP-0495265-A1 | Acid-labile linker molecules | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |