Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 3/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207832 | 0.90 | MEN1 (0.41) | MEN1KMT2AMMP2HPGDSMN1; SMN2 | |
| SCHEMBL7105161 | 0.87 | MEN1 (0.40) | MEN1KMT2AMMP2HPGDSMN1; SMN2 | |
| SCHEMBL4265208 | 0.87 | NPC1 (0.47) | MMP2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7214212 | 0.87 | NPC1 (0.47) | MMP2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7212742 | 0.84 | HPRT1 (0.39) | KMT2AANPEPERAP1ERAP2 | |
| SCHEMBL7026839 | 0.81 | ELANE (0.41) | MEN1KMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7701970 | 0.76 | NPC1 (0.45) | MMP2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL5142558 | 0.76 | NPC1 (0.45) | MMP2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL7208522 | 0.74 | NPC1 (0.44) | NPC1RAB9A | |
| SCHEMBL7209093 | 0.74 | CA1 (0.60) | MEN1KMT2ALMNAMMP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |