Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105161 | 0.90 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2HTTHPGD | |
| SCHEMBL7207845 | 0.90 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2HTTHPGD | |
| SCHEMBL7701970 | 0.86 | NPC1 (0.45) | CA1CA2MMP2CA9TSHR | |
| SCHEMBL5142558 | 0.86 | NPC1 (0.45) | CA1CA2MMP2CA9TSHR | |
| SCHEMBL7026839 | 0.83 | ELANE (0.41) | MEN1KMT2ASMN1; SMN2HTTHPGD | |
| SCHEMBL7209101 | 0.83 | PIN1 (0.40) | KMT2ATDP1CA12CA1CA2 | |
| SCHEMBL7701967 | 0.76 | NPC1 (0.46) | MEN1KMT2ACA1CA2MMP2 | |
| SCHEMBL4265208 | 0.76 | NPC1 (0.47) | SMN1; SMN2CA1CA2MMP2CA9 | |
| SCHEMBL4282571 | 0.76 | CA1 (0.46) | CA1CA2MMP2CA9TSHR | |
| SCHEMBL4282703 | 0.76 | CA1 (0.46) | CA1CA2MMP2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |