SCHEMBL7207863

SCHEMBL7207863

O=C(CN1C[CH]CC1)c1cccc(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
GLA P06280 1/20 0.46
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA6 P23280 1/20 0.42
CA9 Q16790 1/20 0.42
CTNNB1 P35222 1/20 0.42
KDM4E B2RXH2 2/20 0.41
ALPL P05186 2/20 0.41
ALPG P10696 1/20 0.41
PARP1 P09874 1/20 0.41
KMT2A Q03164 1/20 0.41
EGLN2 Q96KS0 1/20 0.39
MAPT P10636 1/20 0.39
MGLL Q99685 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HBB P68871 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6398248 0.83 ALDH1A1 (0.57) ALDH1A1KDM4EKMT2AMAPTHPGD
SCHEMBL7208414 0.81 GRIN2B (0.47) ALDH1A1KDM4EALPLALPGKMT2A
SCHEMBL6403309 0.81 ALPG (0.64) ALDH1A1KDM4EALPLALPGKMT2A
SCHEMBL7391718 0.75 DRD4 (0.47) CTNNB1KDM4E
SCHEMBL6399622 0.74 TSHR (0.52) ALDH1A1KDM4EKMT2AHPGDHSD17B10
SCHEMBL6400119 0.74 CYP19A1 (0.44) ALDH1A1KDM4EALPLALPGKMT2A
SCHEMBL6396604 0.74 KMT2A (0.62) ALDH1A1KDM4EKMT2AMAPTHPGD
SCHEMBL6399913 0.74 MGAM (0.44) ALDH1A1CA12CA1CA2CA6
SCHEMBL11026303 0.73 ALDH1A1 (0.65) ALDH1A1KDM4EKMT2AMAPTHPGD
SCHEMBL6400029 0.71 ALDH1A1 (0.65) ALDH1A1KDM4EKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757051-B1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME DAIICHI SUNTORY PHARMA CO LTD (JP) 2003-10-29 EP disclosed
US-6051569-A 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same SUNTORY LIMITED (JP) 2000-04-18 US disclosed
EP-0774465-A1 Penem derivatives and antimicrobial agents containing the same SUNTORY LIMITED (JP) 1997-05-21 EP disclosed
EP-0757051-A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME SUNTORY LIMITED (JP) 1997-02-05 EP disclosed