SCHEMBL6403309

SCHEMBL6403309

O=C(CN1C[CH]CC1)c1ccc(O)c(O)c1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALPG P10696 10/20 0.64
ALPL P05186 8/20 0.64
NSD2 O96028 5/20 0.52
GAA P10253 4/20 0.52
PLAA Q9Y263 6/20 0.51
POLB P06746 3/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
RECQL P46063 1/20 0.50
KMT2A Q03164 2/20 0.48
GFER P55789 2/20 0.47
MEN1 O00255 1/20 0.47
ALPI P09923 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7208414 0.83 GRIN2B (0.47) ALPGALPLGAAPOLBKDM4E
SCHEMBL7207863 0.81 ALDH1A1 (0.46) ALPGALPLNSD2GAAKDM4E
SCHEMBL6400119 0.78 CYP19A1 (0.44) ALPGALPLPOLBKDM4EALDH1A1
SCHEMBL6399622 0.78 TSHR (0.52) GAAKDM4EALDH1A1KMT2AMEN1
SCHEMBL6396604 0.78 KMT2A (0.62) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL6398248 0.78 ALDH1A1 (0.57) POLBKDM4EALDH1A1MAPTKMT2A
SCHEMBL9356659 0.77 ALPG (0.70) ALPGALPLNSD2GAAPLAA
SCHEMBL6399913 0.75 MGAM (0.44) GAAKDM4EALDH1A1MAPTKMT2A
SCHEMBL6400029 0.75 ALDH1A1 (0.65) POLBKDM4EALDH1A1MAPTKMT2A
SCHEMBL7388115 0.74 ALPL (0.48) ALPGALPLGAAPLAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050004092-A1 Penem derivatives and antimicrobial agent containing the same DAIICHI SUNTORY PHARMA CO., LTD. (JP) 2005-01-06 US disclosed
EP-0757051-B1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME DAIICHI SUNTORY PHARMA CO LTD (JP) 2003-10-29 EP disclosed
EP-0757051-A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME SUNTORY LIMITED (JP) 1997-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004092-A1 Penem derivatives and antimicrobial agent containing the same MRPL21, MRPS2, MRPS28 ALPG 3369/4885ALPL 1957/4885NSD2 2747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.