Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157371 | 0.92 | MAPK1 (0.51) | MAPK1HIF1ATDP1SLC6A3CYP2D6 | |
| SCHEMBL157372 | 0.92 | MAPK1 (0.44) | MAPK1HIF1ATDP1SLC6A3CYP2D6 | |
| SCHEMBL16047488 | 0.89 | MAPK1 (0.42) | MAPK1HIF1ATDP1SLC6A3CYP2D6 | |
| SCHEMBL16047490 | 0.89 | MAPK1 (0.49) | MAPK1HIF1ATDP1SLC6A3CYP2D6 | |
| SCHEMBL7630229 | 0.87 | CYP2D6 (0.43) | MAPK1HIF1ATDP1SLC6A3CYP2D6 | |
| SCHEMBL272635 | 0.87 | CYP2D6 (0.43) | MAPK1HIF1ATDP1SLC6A3CYP2D6 | |
| SCHEMBL1986305 | 0.85 | MEN1 (0.47) | MAPK1HIF1ATDP1CYP2D6SCN1A | |
| SCHEMBL27905119 | 0.84 | KMT2A (0.50) | TDP1SLC6A3ALDH1A1KMT2AADRB2 | |
| SCHEMBL721537 | 0.82 | MAPK1 (0.57) | MAPK1HIF1ATDP1SLC6A3CYP2D6 | |
| SCHEMBL16044767 | 0.81 | ALDH1A1 (0.42) | MAPK1HIF1ATDP1SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 859 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109795-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2026-04-23 | — | — | US | claimed |
| EP-4598999-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | Eastman Chemical Company (US) | 2025-08-13 | — | — | EP | claimed |
| US-12365785-B2 | Glycol ether aryl ester plasticizer | EASTMAN CHEMICAL COMPANY (US) | 2025-07-22 | — | — | US | claimed |
| WO-2024076953-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2024-04-11 | — | — | WO | claimed |
| CN-115975075-A | Catalyst component for olefin polymerization, catalyst and application | 中国石油化工股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-111907155-B | Intermediate film and laminated glass comprising same | 长春石油化学股份有限公司 | 2023-01-24 | — | — | CN | claimed |
| US-20220227962-A1 | GLYCOL ETHER ARYL ESTER PLASTICIZER | EASTMAN CHEMICAL COMPANY (US) | 2022-07-21 | — | — | US | claimed |
| EP-3990532-A1 | GLYCOL ETHER ARYL ESTER PLASTICIZER | Eastman Chemical Company (US) | 2022-05-04 | — | — | EP | claimed |
| US-20210028444-A1 | THIN FILM CERAMICS THAT OFFER ELECTRIC AND ELECTROCHEMICAL PROPERTIES USING NANOPOWDERS OF CONTROLLED COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-01-28 | — | — | US | claimed |
| WO-2021010911-A1 | AN EASILY APPLICABLE HYDROPHOBIC COATING COMPOSITION TO IMPROVE MOISTURE AND WATER RESISTANCE OF THE LOCKING SYSTEMS OF THE LAMINATE FLOORING PARQUETS | AGT AĞAÇ SANAYİ VE TİCARET ANONİM ŞİRKETİ (TR) | 2021-01-21 | — | — | WO | claimed |
| EP-0907679-A4 | AUTOMOTIVE ADDITIVES AND SEALANTS CONTAINING WASTE POWDER PRIME | HENKEL CORP (US) | 2000-08-23 | — | — | EP | claimed |
| EP-0907679-A1 | AUTOMOTIVE ADDITIVES AND SEALANTS CONTAINING WASTE POWDER PRIME | HENKEL CORPORATION (US) | 1999-04-14 | — | — | EP | claimed |
| US-5710199-A | WASTE POWDER PRIME, PLASTICIZERS, ETHYLHEXYL DIPHENYL PHOSPHATE, PHTHALATE AND ESTERS | HENKEL CORPORATION | 1998-01-20 | — | — | US | claimed |
| EP-0673916-B1 | Preparation of 2,2,4-trimethyl-1,3-pentanediol dibenzoate and di(alkyl-substituted) benzoates | VELSICOL CHEMICAL CORP (US) | 1998-01-07 | — | — | EP | claimed |
| WO-1997048763-A1 | AUTOMOTIVE ADDITIVES AND SEALANTS CONTAINING WASTE POWDER PRIME | HENKEL CORPORATION (US) | 1997-12-24 | — | — | WO | claimed |
| EP-0416822-B1 | Stain-resistant plasticizer compositions and method of making same | VELSICOL CHEMICAL CORP (US) | 1996-03-13 | — | — | EP | claimed |
| EP-0673916-A1 | Preparation of 2,2,4-trimethyl-1,3-pentanediol dibenzoate and di(alkyl-substituted) benzoates | VELSICOL CHEMICAL CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| US-5153342-A | Esterification of 2,2,4-trimethyl-1,3-pentanediol with (alkyl) benzoic acids using basic catalysts | HULS AMERICA INC. (US) | 1992-10-06 | — | — | US | claimed |
| US-5039728-A | Floor and wall coverings; vinly chloride homo- and copolymers | HULS AMERICA INC. (US) | 1991-08-13 | — | — | US | claimed |
| EP-0416822-A2 | Stain-resistant plasticizer compositions and method of making same | VELSICOL CHEMICAL CORPORATION (US) | 1991-03-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365785-B2 | Glycol ether aryl ester plasticizer | DAGLA, DDT, PPARG | MAPK1 1891/4885HIF1A 908/4885TDP1 1253/4885 |
| US-20220227962-A1 | GLYCOL ETHER ARYL ESTER PLASTICIZER | DAGLA, DDT, PPARG | MAPK1 1891/4885HIF1A 908/4885TDP1 1253/4885 |
| US-20260109795-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | TRIM4, TRIM58, TRA2B | MAPK1 4017/4885HIF1A 1104/4885TDP1 3004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.