Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280512 | 0.93 | XIAP (0.48) | OPRM1OPRK1F2PRSS1XIAP | |
| SCHEMBL2192304 | 0.90 | OPRM1 (0.49) | OPRM1OPRK1F2 | |
| SCHEMBL7418654 | 0.90 | OPRM1 (0.49) | OPRM1OPRK1F2 | |
| SCHEMBL5597616 | 0.90 | OPRM1 (0.49) | OPRM1OPRK1F2 | |
| SCHEMBL5597620 | 0.90 | OPRM1 (0.49) | OPRM1OPRK1F2 | |
| SCHEMBL11013694 | 0.90 | F2 (0.60) | F2PRSS1ACE | |
| SCHEMBL11013687 | 0.90 | F2 (0.60) | F2PRSS1ACE | |
| SCHEMBL2193283 | 0.90 | OPRM1 (0.48) | OPRM1OPRK1 | |
| SCHEMBL8258695 | 0.87 | F2 (0.53) | OPRM1OPRK1F2PRSS1ACE | |
| SCHEMBL2182404 | 0.87 | F2 (0.47) | OPRM1OPRK1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610270-B1 | Determining the rate of substrate-product conversion for gateway enzymes important to therapy management, using labelled metaprobes | XANTHUS LIFE SCIENCES, INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1089765-A2 | $i(IN VIVO) DETERMINATION OF METABOLIC FUNCTION FOR USE IN THERAPY MANAGEMENT | Phenome Sciences Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000636-A2 | IN VIVO DETERMINATION OF METABOLIC FUNCTION FOR USE IN THERAPY MANAGEMENT | PHENOME SCIENCES INC. (US) | 2000-01-06 | — | — | WO | disclosed |