Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781419 | 0.82 | NOS2 (0.39) | NOS2NOS3NOS1PRCPDPP4 | |
| SCHEMBL15391851 | 0.82 | PRCP (0.41) | NOS2NOS3NOS1PRCPDPP4 | |
| SCHEMBL84845 | 0.82 | PRCP (0.41) | NOS2NOS3NOS1PRCPDPP4 | |
| SCHEMBL3771163 | 0.82 | NOS2 (0.39) | NOS2NOS3NOS1PRCPDPP4 | |
| SCHEMBL19502428 | 0.82 | PRCP (0.41) | NOS2NOS3NOS1PRCPDPP4 | |
| SCHEMBL3781423 | 0.82 | NOS2 (0.39) | NOS2NOS3NOS1PRCPDPP4 | |
| SCHEMBL7782161 | 0.82 | PRCP (0.41) | NOS2NOS3NOS1PRCPDPP4 | |
| SCHEMBL3771160 | 0.82 | NOS2 (0.39) | NOS2NOS3NOS1PRCPDPP4 | |
| SCHEMBL28015154 | 0.82 | PRCP (0.39) | NOS2NOS3NOS1PRCPDPP4 | |
| Hydrochloric Acid SCHEMBL29401738 | 0.81 | PRCP (0.41) | NOS2NOS3NOS1PRCPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613738-B1 | Comprising 1,2-dihydroxy-homotyrosine, 4-hydroxyproline, threonine, glutamine, 3-,4-dihydroxymethylproline, 4,5-dihydroxyornithine and lipid | HMV CORPORATION | 2003-09-02 | — | — | US | disclosed |
| WO-2000009735-A1 | A CYCLIC LIPOPEPTIDE FROM CRYPTOSPORIOPSIS QUERCINA POSSESSING ANTIFUNGAL ACTIVITY | STROBEL GARY A (US) | 2000-02-24 | — | — | WO | disclosed |