Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 4/20 | 0.37 |
| ▸ | PRKCB | P05771 | 4/20 | 0.37 |
| ▸ | PRKCA | P17252 | 4/20 | 0.37 |
| ▸ | PRKCH | P24723 | 4/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.37 |
| ▸ | PRKCI | P41743 | 3/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26970651 | 0.82 | PBRM1 (0.45) | KAT8PPARALMNAGPR3LPL | |
| SCHEMBL10523260 | 0.80 | MAOA (0.48) | KAT8PPARAGPR3LPLLIPG | |
| SCHEMBL7208510 | 0.79 | HTR2A (0.46) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL3839761 | 0.76 | PBRM1 (0.47) | ALDH1A1HSD17B10 | |
| SCHEMBL27473293 | 0.74 | SLC6A2 (0.42) | KAT8PPARALMNAGPR3LPL | |
| SCHEMBL7212153 | 0.72 | HTR2A (0.40) | LMNAS1PR1ESR1ADRA2AADORA3 | |
| SCHEMBL16682971 | 0.71 | KAT8 (0.41) | KAT8PPARALMNAGPR3LPL | |
| SCHEMBL4897218 | 0.71 | SLC6A2 (0.51) | KAT8PPARALMNAGPR3LPL | |
| SCHEMBL4895890 | 0.71 | SLC6A2 (0.51) | KAT8PPARALMNAGPR3LPL | |
| SCHEMBL4896260 | 0.71 | SLC6A2 (0.51) | KAT8PPARALMNAGPR3LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610877-B1 | Treating photo and/or age damaged skin | HOFFMAN-LA ROCHE INC. | 2003-08-26 | — | — | US | disclosed |
| EP-0641759-B1 | Use of aromatic carboxylic derivatives for the preparation of drugs | HOFFMANN LA ROCHE (CH) | 1998-12-09 | — | — | EP | disclosed |
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0641759-A1 | Aromatic carboxylic acid derivatives, their preparation and drugs containing these derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-03-08 | — | — | EP | disclosed |