Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.76 |
| ▸ | GAA | P10253 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5621395 | 0.86 | CYP2C9 (1.00) | LMNACYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL3882476 | 0.82 | CYP2C9 (0.82) | LMNACYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL3880856 | 0.79 | CYP2C9 (0.69) | LMNACYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL28794517 | 0.76 | CYP2C9 (0.64) | LMNACYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL16429648 | 0.73 | KDM4E (0.59) | LMNAALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL13791149 | 0.71 | CYP2C9 (0.65) | LMNACYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL4129933 | 0.71 | CYP2C9 (0.58) | LMNACYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL24358070 | 0.69 | LMNA (0.53) | LMNACYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL13791801 | 0.69 | CYP2C9 (0.56) | LMNACYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL27852359 | 0.69 | CYP2C9 (0.55) | LMNACYP2C9CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055093-A1 | Acylated indanyl amines and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055093-A1 | Acylated indanyl amines and their use as pharmaceuticals | EDNRA, VEGFA, EDNRB | LMNA 1843/4885CYP2C9 1282/4885CYP2C19 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.