Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.94 |
| ▸ | PPARG | P37231 | 7/20 | 0.94 |
| ▸ | PPARD | Q03181 | 7/20 | 0.94 |
| ▸ | PPARA | Q07869 | 7/20 | 0.94 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.94 |
| ▸ | TSHR | P16473 | 4/20 | 0.94 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.94 |
| ▸ | FABP4 | P15090 | 3/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | TLR2 | O60603 | 2/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.94 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.94 |
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | ESR1 | P03372 | 1/20 | 0.94 |
| ▸ | PDE4A | P27815 | 1/20 | 0.94 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nonadecanoic Acid SCHEMBL356183 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL358302 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Arachidic Acid SCHEMBL6138833 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL21391850 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL21391852 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL7208286 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL7208279 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL3964568 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL324624 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL324541 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305469-A2 | NEW PROCESS FOR PRE-TREATING CELLULOSIC FIBERS AND CELLULOSIC FIBER BLENDS | CLARIANT INTERNATIONAL LTD. (CH) | 2003-05-02 | — | — | EP | claimed |
| WO-2001046518-A2 | NEW PROCESS FOR PRE-TREATING CELLULOSIC FIBERS AND CELLULOSIC FIBER BLENDS | CLARIANT INTERNATIONAL LTD. (CH) | 2001-06-28 | — | — | WO | claimed |
| CN-112384189-A | Pristine graphene for skin care and composition with natural pressure sensitive adhesive | 生物自然实验室有限公司 | 2021-02-19 | — | — | CN | disclosed |
| US-10907033-B2 | Processing additive mixtures | LANXESS DEUTSCHLAND GMBH (DE) | 2021-02-02 | — | — | US | disclosed |
| US-10723670-B2 | Blasting compositions | Dyno Nobel Asia Pacific Pty Limited (AU) | 2020-07-28 | — | — | US | disclosed |
| CN-109641433-A | Laminated sheet and method for producing same | 日本瑞翁株式会社 | 2019-04-16 | — | — | CN | disclosed |
| US-20190031863-A1 | NEW PROCESSING ADDITIVE MIXTURES | LANXESS DEUTSCHLAND GMBH (DE) | 2019-01-31 | — | — | US | disclosed |
| CN-109072020-A | self-adhesive layer | 日本瑞翁株式会社 | 2018-12-21 | — | — | CN | disclosed |
| CN-107001870-A | Adhesive sheet for portable electronic device | 日东电工株式会社 | 2017-08-01 | — | — | CN | disclosed |
| CN-107001871-A | Adhesive sheet | 日东电工株式会社 | 2017-08-01 | — | — | CN | disclosed |
| CN-107001869-A | Adhesive sheet | 日东电工株式会社 | 2017-08-01 | — | — | CN | disclosed |
| CN-104419037-B | Foamed sheet | 日东电工株式会社 | 2016-09-14 | — | — | CN | disclosed |
| CN-105745262-A | Foam sheet | 日东电工株式会社 | 2016-07-06 | — | — | CN | disclosed |
| CN-105745263-A | Foamed sheet | 日东电工株式会社 | 2016-07-06 | — | — | CN | disclosed |
| US-20140311634-A1 | BLASTING COMPOSITIONS | Dyno Nobel Asia Pacific Pty Limited (AU) | 2014-10-23 | — | — | US | disclosed |
| EP-2780302-A1 | BLASTING COMPOSITIONS | Dyno Nobel Asia Pacific Pty Limited (AU) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013071363-A1 | BLASTING COMPOSITIONS | DYNO NOBEL ASIA PACIFIC PTY LTD (AU) | 2013-05-23 | — | — | WO | disclosed |
| US-4302378-A | GRAFT POLYMER WITH A THERMOPLASTIC RESIN AND A PERFLUOROALKANE ACID OR DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | disclosed |