SCHEMBL7208469

SCHEMBL7208469

C[S+]([O-])c1ccc(CNc2cccc(NCc3ccc(F)cc3Cl)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
GAA P10253 2/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 1/20 0.39
PPARA Q07869 1/20 0.39
MAOB P27338 1/20 0.38
BRD4 O60885 1/20 0.38
TP53 P04637 1/20 0.37
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
KDM4E B2RXH2 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6691549 0.82 TP53 (0.48) MAPTKMT2AMEN1LMNAMAOB
SCHEMBL6693433 0.81 BRD4 (0.49) MAPTKMT2AMEN1GAALMNA
SCHEMBL6695981 0.78 LMNA (0.51) MAPTKMT2AMEN1GAARAB9A
SCHEMBL7202078 0.78 MEN1 (0.37) MAPTKMT2AMEN1PPARAHPGD
SCHEMBL6693953 0.75 MAPT (0.65) MAPTKMT2AMEN1GAALMNA
SCHEMBL7207001 0.74 CA1 (0.47) MAPTKMT2AMEN1GAARAB9A
SCHEMBL30339804 0.74 L3MBTL1 (0.50) MAPTKMT2AMEN1RAB9ALMNA
SCHEMBL6692354 0.72 PPARA (0.54) MAPTKMT2AMEN1PPARAMAOB
SCHEMBL6694596 0.70 TP53 (0.54) MAPTKMT2AMEN1RAB9ALMNA
SCHEMBL10055035 0.69 HPGD (0.67) MAPTKMT2AMEN1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003076388-A2 BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS 4SC AG (DE) 2003-09-18 WO disclosed