Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 8/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200984 | 0.76 | AKR1C3 (0.56) | AKR1C3AKR1C2AKR1C4PTGS1ABCB1 | |
| SCHEMBL20769675 | 0.76 | AKR1C3 (0.72) | AKR1C3AKR1C2ALDH1A1AKR1C4PTGS1 | |
| SCHEMBL28977346 | 0.74 | AKR1C3 (0.49) | AKR1C3AKR1C2ALDH1A1AKR1C4PTGS1 | |
| SCHEMBL27474952 | 0.71 | AKR1C3 (0.59) | AKR1C3AKR1C2ALDH1A1AKR1C4PTGS1 | |
| SCHEMBL4216463 | 0.71 | AKR1C3 (0.58) | AKR1C3AKR1C2ALDH1A1AKR1C4PTGS1 | |
| SCHEMBL7928065 | 0.71 | AKR1C3 (0.53) | AKR1C3AKR1C2ALDH1A1HPGDAKR1C4 | |
| SCHEMBL8606260 | 0.70 | AKR1C3 (0.83) | AKR1C3AKR1C2AKR1C4PTGS1ABCB1 | |
| SCHEMBL6168330 | 0.70 | AKR1C3 (0.44) | AKR1C3AKR1C2ALDH1A1AKR1C4PTGS1 | |
| SCHEMBL6171169 | 0.70 | AKR1C3 (0.46) | AKR1C3AKR1C2ALDH1A1AKR1C4PTGS1 | |
| SCHEMBL9153676 | 0.69 | AKR1C3 (0.50) | AKR1C3AKR1C2ALDH1A1AKR1C4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |