Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169913 | 0.82 | MCL1 (0.65) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL9814781 | 0.78 | MAPT (0.53) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL18227958 | 0.77 | HTT (0.52) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL2187877 | 0.76 | MCL1 (0.62) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL19283631 | 0.76 | MAPT (0.50) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL10500501 | 0.76 | MAPT (0.50) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL9879522 | 0.73 | MCL1 (0.42) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL14867413 | 0.72 | MCL1 (0.53) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL4875427 | 0.72 | MAPT (0.50) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL11451081 | 0.71 | MAPT (1.00) | MAPTHTTALOX15HBBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252298-B1 | CERTAIN 2-BENZOYL-1,3,5-CYCLOHEXANETRIONES | STAUFFER CHEMICAL COMPANY (US) | 1991-10-16 | — | — | EP | claimed |
| JP-63002948-A | — | — | None | — | — | JP | disclosed |
| EP-0966453-B1 | SACCHARINE-5-CARBONYL-CYCLOHEXANE-1,3,5-TRIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-6083880-A | Saccharine-5-carbonyl-cyclohexane-1, 3, 5-trione derivatives, their preparation and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-04 | — | — | US | disclosed |
| US-5210312-A | Preparing herbicidal tetraalkyl cyclohexan-1,3,5-triones from unalkylated benzenetriols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-11 | — | — | US | disclosed |
| US-5085688-A | Certain 2-(2-chloro-3-alkoxy-4-substituted benzoyl)-5-methyl-5-1,3-cyclohexanediones as herbicides | ICI AMERICAS INC. (US) | 1992-02-04 | — | — | US | disclosed |
| EP-0252298-B1 | CERTAIN 2-BENZOYL-1,3,5-CYCLOHEXANETRIONES | STAUFFER CHEMICAL COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0252298-B1 | CERTAIN 2-BENZOYL-1,3,5-CYCLOHEXANETRIONES | STAUFFER CHEMICAL COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| WO-1991013547-A1 | HERBICIDAL COMPOSITIONS OF AROYLATED 1,3-DICARBONYL OR 1,3,5-TRICARBONYL CYCLOHEXANE HERBICIDES AND TWO-PART ANTIDOTE SYSTEM THEREFOR | AHLE JAMES L (US) | 1991-09-19 | — | — | WO | disclosed |
| WO-1991013548-A1 | HERBICIDAL COMPOSITIONS OF AROYLATED 1,3-DICARBONYL OR 1,3,5-TRICARBONYL CYCLOHEXANE HERBICIDES AND AN ANTIDOTE SYSTEM THEREFOR | AHLE JAMES L (US) | 1991-09-19 | — | — | WO | disclosed |
| US-4806146-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0298679-A2 | Herbicidal compositions of acylated 1,3,5-tricarbonyl cyclohexane herbicides and antidotes therefor | ICI AMERICAS INC. (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4797150-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-4780127-A | Certain 2-(substituted benzoyl)-1,3-cyclohexanediones and their use as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0283152-A2 | Process for the preparation of substituted cyclohexane-1,3,5-triones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-21 | — | — | EP | disclosed |
| EP-0252298-A3 | CERTAIN 2-BENZOYL-1,3,5-CYCLOHEXANETRIONES | — | 1988-06-29 | — | — | EP | disclosed |
| EP-0252298-A2 | Certain 2-benzoyl-1,3,5-cyclohexanetriones | STAUFFER CHEMICAL COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| EP-0252298-A2 | Certain 2-benzoyl-1,3,5-cyclohexanetriones | STAUFFER CHEMICAL COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| JP-S632948-A | 2-BENZOYL-1,3,5-CYCLOHEXANETRIONES AND SALTS | STAUFFER CHEMICAL CO | 1988-01-07 | — | — | JP | disclosed |
| US-4695673-A | Process for the production of acylated 1,3-dicarbonyl compounds | STAUFFER CHEMICAL COMPANY (US) | 1987-09-22 | — | — | US | disclosed |