Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466743 | 0.84 | MAPT (0.49) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL169913 | 0.73 | MCL1 (0.65) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL23732677 | 0.72 | ALDH1A1 (0.36) | MAPTALOX15ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL9711454 | 0.72 | MAPT (0.44) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL8623240 | 0.72 | MCL1 (0.49) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL8623238 | 0.72 | MCL1 (0.49) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL16597881 | 0.72 | MAPT (0.55) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL7208671 | 0.72 | MAPT (0.55) | MAPTHTTALOX15HBBMCL1 | |
| SCHEMBL9814781 | 0.70 | MAPT (0.53) | MAPTHTTALOX15HBBMCL1 | |
| Hydrochloric Acid SCHEMBL29974591 | 0.70 | MAPT (0.41) | MAPTHTTALOX15HBBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001401-A1 | HERBICIDAL AND INSECTICIDAL 3-BENZOYL-PYRROLIDIN-2,4-DIONE DERIVATES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-20 | — | — | WO | claimed |
| EP-1997803-B1 | A TECHNIQUE FOR MODIFICATION OF A BIO-PRODUCT MOLECULE AND APPLICATION OF WEED CONTROL | UNIV NANJING AGRICULTURAL (CN) | 2018-02-14 | — | — | EP | disclosed |
| US-9468209-B2 | Method for eradicating weeds with derivatives of 3-acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one | NANJING AGRICULTURAL UNIVERSITY (CN) | 2016-10-18 | — | — | US | disclosed |
| US-20150141254-A1 | METHOD FOR ERADICATING WEEDS WITH DERIVATIVES OF 3-ACETYL-5-SEC-BUTYL-4-HYDROXY-3-PYRROLIN-2-ONE | NANJING AGRICULTURAL UNIVERSITY (CN) | 2015-05-21 | — | — | US | disclosed |
| US-8921274-B2 | Method for eradicating weeds with derivatives of 3-acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one | NANJING AGRICULTURAL UNIVERSITY (CN) | 2014-12-30 | — | — | US | disclosed |
| CN-103922990-A | Method for molecular modification and weed control of biological source compound | UNIV NANJING AGRICULTURAL | 2014-07-16 | — | — | CN | disclosed |
| US-20120172226-A1 | METHOD FOR ERADICATING WEEDS WITH DERIVATIVES OF 3-ACETYL-5-SEC-BUTYL-4-HYDROXY-3-PYRROLIN-2-ONE | Nantong Jiangshan Agrochemical & Cheimcal Limited Liability Co., Ltd. (CN) | 2012-07-05 | — | — | US | disclosed |
| EP-1997803-A1 | A TECHNIQUE FOR MODIFICATION OF A BIO-PRODUCT MOLECULE AND APPLICATION OF WEED CONTROL | Nanjing Agricultural University (CN) | 2008-12-03 | — | — | EP | disclosed |
| US-20080176748-A1 | derived from 3-acetyl-4-hydroxy-5-sec-butylpyrroline-2-ketone, a natural substance, and their potential use in agriculture for weed control | NANJING AGRICULTURAL UNIVERSITY (CN) | 2008-07-24 | — | — | US | disclosed |
| WO-1994001401-A1 | HERBICIDAL AND INSECTICIDAL 3-BENZOYL-PYRROLIDIN-2,4-DIONE DERIVATES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172226-A1 | METHOD FOR ERADICATING WEEDS WITH DERIVATIVES OF 3-ACETYL-5-SEC-BUTYL-4-HYDROXY-3-PYRROLIN-2-ONE | NOTUM, PGA5, ALG1 | MAPT 3894/4885HTT 2191/4885ALOX15 32/4885 |
| US-20080176748-A1 | derived from 3-acetyl-4-hydroxy-5-sec-butylpyrroline-2-ketone, a natural substance, and their potential use in agriculture for weed control | HADH, HADHB, ABAT | MAPT 2355/4885HTT 839/4885ALOX15 1999/4885 |
| US-20150141254-A1 | METHOD FOR ERADICATING WEEDS WITH DERIVATIVES OF 3-ACETYL-5-SEC-BUTYL-4-HYDROXY-3-PYRROLIN-2-ONE | NOTUM, HDAC6, PGA5 | MAPT 3521/4885HTT 2081/4885ALOX15 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.