SCHEMBL7208897

SCHEMBL7208897

CNC(=O)c1cc2ccccc2oc1=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.72
MAOA P21397 7/20 0.71
KDM4E B2RXH2 2/20 0.69
CA12 O43570 2/20 0.69
CA9 Q16790 2/20 0.69
CYP1A2 P05177 1/20 0.69
NT5E P21589 1/20 0.69
F12 P00748 1/20 0.68
ALDH1A1 P00352 1/20 0.68
HPGD P15428 1/20 0.68
NPC1 O15118 1/20 0.67
RAB9A P51151 1/20 0.67
CA1 P00915 1/20 0.66
CA3 P07451 1/20 0.66
TSHR P16473 1/20 0.66
CA4 P22748 1/20 0.66
CA6 P23280 1/20 0.66
CA5A P35218 1/20 0.66
CA7 P43166 1/20 0.66
GPR35 Q9HC97 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13448131 0.84 MAOB (0.67) MAOBMAOAKDM4EF12ALDH1A1
SCHEMBL30214896 0.84 MAOB (1.00) MAOBMAOAKDM4ECA12CA9
SCHEMBL4390923 0.84 MAOB (1.00) MAOBMAOAKDM4ECA12CA9
SCHEMBL15058644 0.83 MAOB (0.73) MAOBMAOAKDM4EALDH1A1NPC1
SCHEMBL14176761 0.83 MAOB (1.00) MAOBMAOAKDM4ECA12CA9
SCHEMBL11462954 0.83 MAOB (0.91) MAOBMAOACA12F12NPC1
SCHEMBL76133 0.83 MAOB (0.75) MAOBMAOAKDM4EF12ALDH1A1
3-Acetylcoumarin SCHEMBL181862 0.81 MAOB (1.00) MAOBMAOAKDM4ECA12CA9
3-Acetylcoumarin SCHEMBL31097378 0.81 MAOB (1.00) MAOBMAOAKDM4ECA12CA9
SCHEMBL831792 0.81 MAOB (1.00) MAOBMAOAF12NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0856065-B1 ASSAY METHODS AND KITS FOR DIAGNOSING AUTOIMMUNE DISEASE UNIV NEBRASKA (US) 2003-06-25 EP claimed
US-7282575-B2 Functional peptide nucleic acid monomer and process for producing the same CREDIA JAPAN CO., LTD. (JP) 2007-10-16 US disclosed