Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 7/20 | 0.39 |
| ▸ | XIAP | P98170 | 3/20 | 0.39 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1718165 | 0.94 | XIAP (0.47) | HTTELANEXIAPMLXDPP4 | |
| SCHEMBL4408100 | 0.84 | CMA1 (0.44) | ELANEMEN1KMT2A | |
| SCHEMBL2769300 | 0.80 | XIAP (0.44) | PREPELANEXIAPMLXCYP3A4 | |
| SCHEMBL8344004 | 0.77 | DPP4 (0.46) | HTTDPP4DPP8DPP9KCNH2 | |
| SCHEMBL2768336 | 0.77 | DPP4 (0.50) | PREPELANEXIAPMLXDPP4 | |
| SCHEMBL30052033 | 0.77 | ACE (0.51) | XIAPDPP4DPP8DPP9MEN1 | |
| Bromide SCHEMBL1509660 | 0.76 | DPP4 (0.49) | PREPELANEXIAPMLXDPP4 | |
| Trifluoroacetic Acid SCHEMBL1509589 | 0.75 | XIAP (0.53) | ELANEXIAPMLXMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL27641390 | 0.75 | XIAP (0.53) | ELANEXIAPMLXMEN1KMT2A | |
| SCHEMBL13380009 | 0.75 | XIAP (0.47) | ELANEXIAPMLXDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030148961-A1 | Peptidyl ketones as inhibitors of DPIV | PROSIDION LIMITED (GB) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030148961-A1 | Peptidyl ketones as inhibitors of DPIV | GLS, SLC5A1, BCKDK | HTT 3945/4885HSPA9 378/4885PREP 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.