Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 8/20 | 0.48 |
| ▸ | KDM5A | P29375 | 5/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208695 | 0.95 | LSS (0.43) | LSSKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7210575 | 0.83 | LSS (0.37) | LSSKDM5AKDM4CCYP2D6ALDH1A1 | |
| SCHEMBL7204660 | 0.83 | LSS (0.37) | LSSKDM5AKDM4CCYP2D6ALDH1A1 | |
| SCHEMBL7205511 | 0.81 | AVPR1B (0.37) | LSSKDM5AKDM4CCYP2D6ALDH1A1 | |
| SCHEMBL7209640 | 0.79 | LSS (0.62) | LSSKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7209635 | 0.79 | LSS (0.62) | LSSKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7212627 | 0.75 | LSS (0.54) | LSSAVPR1BACHE | |
| SCHEMBL25292439 | 0.74 | ALDH1A1 (0.50) | KDM5AKDM4CALDH1A1LMNAARG1 | |
| SCHEMBL7208698 | 0.73 | LSS (0.55) | LSSKDM5APHF8KDM2AKDM4C | |
| SCHEMBL7208701 | 0.73 | LSS (0.55) | LSSKDM5APHF8KDM2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | claimed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | claimed |
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |