SCHEMBL7209745

SCHEMBL7209745

C=C(C(N)=O)C(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
ALDH1A1 P00352 6/20 0.48
MAPT P10636 2/20 0.48
TSHR P16473 1/20 0.48
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GLO1 Q04760 1/20 0.40
CYP2D6 P10635 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
THRB P10828 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
TRPA1 O75762 1/20 0.36
CYP1A2 P05177 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10776235 0.86 ALOX15 (0.46) ALOX15ALDH1A1MAPTTSHRLMNA
SCHEMBL79588 0.85 ALDH1A1 (0.56) ALOX15ALDH1A1MAPTTSHRLMNA
SCHEMBL13269637 0.85 ALDH1A1 (0.56) ALOX15ALDH1A1MAPTTSHRLMNA
SCHEMBL28293945 0.85 ALDH1A1 (0.56) ALOX15ALDH1A1MAPTTSHRLMNA
SCHEMBL28099320 0.82 ALDH1A1 (0.54) ALOX15ALDH1A1MAPTTSHRLMNA
Ammonia Solution, Strong SCHEMBL28294025 0.82 ALDH1A1 (0.54) ALOX15ALDH1A1MAPTTSHRLMNA
SCHEMBL994739 0.80
SCHEMBL527427 0.79
SCHEMBL150289 0.78 ALDH1A1 (0.55) ALOX15ALDH1A1MAPTTSHRLMNA
SCHEMBL11265522 0.78 TDP1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4185624-A1 RELEASE COATING COMPRISING WATERBORNE LATEX POLYMER COMPRISING POLYMERIZED SURFACTANT 3M Innovative Properties Company (US) 2023-05-31 EP disclosed
EP-1284741-A2 3'-OR 2'-HYDROXYMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATMENT OF HEPATITIS VIRUS INFECTIONS Pharmasset, Ltd. (BB) 2003-02-26 EP disclosed
WO-2001079246-A2 3'-OR 2'-HYDROXYMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATMENT OF HEPATITIS VIRUS INFECTIONS PHARMASSET, LTD. (BB) 2001-10-25 WO disclosed
US-4717739-A BONDING GLASS DELTAGLASS S.A. (CH) 1988-01-05 US disclosed
EP-0108630-B1 RADIATION-CURABLE ADHESIVE COMPOSITIONS DELTAGLASS S.A. (CH) 1987-12-23 EP disclosed
EP-0108630-A2 Radiation-curable adhesive compositions DELTAGLASS S.A. (CH) 1984-05-16 EP disclosed