Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059942 | 0.85 | CYP1A2 (0.51) | CYP3A4CYP2C19MEN1KMT2APOLB | |
| SCHEMBL7056566 | 0.85 | MEN1 (0.50) | ATMHSP90AA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7052548 | 0.82 | MEN1 (0.44) | MEN1KMT2APOLBLMNANPSR1 | |
| SCHEMBL28762296 | 0.79 | POLB (0.65) | ATMHSP90AA1CYP2C19MEN1KMT2A | |
| SCHEMBL7053950 | 0.79 | ALDH1A1 (0.58) | MEN1KMT2APOLBLMNANPSR1 | |
| SCHEMBL7051985 | 0.78 | HSD17B10 (0.50) | CYP3A4CYP2C19MEN1KMT2APOLB | |
| SCHEMBL14263855 | 0.78 | LMNA (0.63) | ATMHSP90AA1CYP3A4CYP2C19MEN1 | |
| SCHEMBL6714089 | 0.76 | ATM (0.55) | ATMHSP90AA1CYP3A4CYP2C19MEN1 | |
| SCHEMBL7052592 | 0.75 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL23317358 | 0.75 | ATM (0.54) | ATMHSP90AA1CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613931-B1 | N-(3-chlorphenyl)-2-cyano-2-phenylacetamide | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-02 | — | — | US | disclosed |