Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211573 | 0.88 | LSS (0.57) | LSSLMNACNR2KMT2AALDH1A1 | |
| SCHEMBL7209669 | 0.87 | LSS (0.58) | LSSLMNACNR2KMT2AALDH1A1 | |
| SCHEMBL7210250 | 0.85 | LSS (0.63) | LSS | |
| SCHEMBL7210243 | 0.85 | LSS (0.63) | LSS | |
| SCHEMBL7205051 | 0.82 | LSS (0.46) | LSSLMNACNR2KMT2AALDH1A1 | |
| SCHEMBL7204703 | 0.75 | CNR2 (0.53) | LSSLMNACNR2KMT2AMEN1 | |
| SCHEMBL5092120 | 0.74 | LSS (0.46) | LSSLMNACNR2KMT2AALDH1A1 | |
| SCHEMBL5070017 | 0.74 | LSS (0.45) | LSSLMNACNR2KMT2AALDH1A1 | |
| SCHEMBL7211570 | 0.72 | LSS (0.80) | LSS | |
| SCHEMBL7211566 | 0.72 | LSS (0.80) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |