Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7210452

CCCCCCCCCCCC(C)(C)OS(=O)(=O)c1ccc(C)cc1.N

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.44
ALDH1A1 P00352 5/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
CYP2C9 P11712 3/20 0.38
CYP2C19 P33261 2/20 0.38
CYP3A4 P08684 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 2/20 0.37
TSHR P16473 2/20 0.37
ALB P02768 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CNR2 P34972 3/20 0.36
PLA2G2C Q5R387 1/20 0.36
KCNH2 Q12809 2/20 0.35
GAA P10253 1/20 0.35
CYP2D6 P10635 1/20 0.35
HTT P42858 1/20 0.35
HIF1A Q16665 1/20 0.35
G6PD P11413 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29142129 0.87 MCHR1 (0.46) MCHR1ALDH1A1SMN1; SMN2CYP2C9CYP2C19
SCHEMBL14778175 0.86 ALDH1A1 (0.42) MCHR1ALDH1A1SMN1; SMN2CYP2C9CYP2C19
SCHEMBL28412955 0.84 TDP1 (0.41) ALDH1A1TSHRTDP1
SCHEMBL9228850 0.81 MCHR1 (0.42) MCHR1ALDH1A1SMN1; SMN2CYP2C9CYP2C19
SCHEMBL17223933 0.79 MCHR1 (0.44) MCHR1ALDH1A1SMN1; SMN2CYP2C9CYP2C19
SCHEMBL8394723 0.79 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL9993581 0.78 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
Ammonia Solution, Strong SCHEMBL11193300 0.78 MCHR1 (0.41) MCHR1ALDH1A1SMN1; SMN2CYP2C9CYP2C19
SCHEMBL15963902 0.77 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2CYP2C9CYP2C19CYP3A4
SCHEMBL2895372 0.77 CA12 (0.40) ALDH1A1CYP2C9CYP2C19CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675117-A1 Bromopropargyl quaternary ammonium compounds having antimicrobial activity ROHM AND HAAS COMPANY (US) 1995-10-04 EP claimed
US-5411933-A Bromopropargyl quarternary ammonium compounds having antimicrobial activity ROHM & HAAS COMPANY (US) 1995-05-02 US claimed
US-6613340-B2 Substantive UV absorbing organic-soluble quaternary salts of cinnamidoalkylamine are described. Hair, skin and fabric care compositions containing the compounds of formula I. GALAXY SURFACTANTS LTD. (IN) 2003-09-02 US disclosed