Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861580 | 0.81 | SIGMAR1 (0.62) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| SCHEMBL14259465 | 0.80 | SIGMAR1 (0.44) | SIGMAR1ADRB2TRPA1TP53CYP1A2 | |
| SCHEMBL14454181 | 0.80 | RIPK1 (0.47) | ADRB2ADRB1TRPA1LMNA | |
| SCHEMBL7895755 | 0.80 | RIPK1 (0.47) | ADRB2ADRB1TRPA1LMNA | |
| SCHEMBL12312530 | 0.80 | RIPK1 (0.47) | ADRB2ADRB1TRPA1LMNA | |
| SCHEMBL7207159 | 0.79 | ADRB3 (0.55) | SIGMAR1ADRB2ADRB1ADRA2BADRA2C | |
| SCHEMBL10526965 | 0.79 | RIPK1 (0.49) | TRPA1 | |
| SCHEMBL21243273 | 0.79 | SIGMAR1 (0.73) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| SCHEMBL9322567 | 0.78 | SIGMAR1 (1.00) | SIGMAR1TAAR1SLC18A2NPC1RAB9A | |
| SCHEMBL21264380 | 0.78 | RIPK1 (0.46) | ADRA2CHTR2AADRA1ATRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924193-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-02-19 | — | — | EP | disclosed |