Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | FOS | P01100 | 7/20 | 0.61 |
| ▸ | JUN | P05412 | 7/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.61 |
| ▸ | RELA | Q04206 | 7/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158474 | 0.90 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL7210767 | 0.88 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL12929684 | 0.87 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL11164512 | 0.87 | NPSR1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL7495639 | 0.87 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL5914410 | 0.86 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL11160403 | 0.86 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL11162029 | 0.86 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL8398530 | 0.85 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL11162706 | 0.85 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1146566-C | 2-aryl-8-oxodihydropurine derivatives, process for producting same, medicinal conty. same, and intermediates thereof | �ձ���ҩ��ʽ���� | 2004-04-21 | — | — | CN | disclosed |
| EP-1036794-B1 | 2-ARYL-8-OXODIHYDROPURINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, MEDICINAL COMPOSITIONS CONTAINING THE SAME, AND INTERMEDIATES THEREOF | DAINIPPON PHARMACEUTICAL CO (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6372740-B1 | NERVOUS SYSTEM DISORDERS, ANTIEPILEPTIC AGENTS AND ANTIDEPRESSANTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2002-04-16 | — | — | US | disclosed |
| CN-1284076-A | 2-aryl-8-oxodihydropurine derivatives, process for producting same, medicinal conty. same, and intermediates thereof | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1036794-A1 | 2-ARYL-8-OXODIHYDROPURINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, MEDICINAL COMPOSITIONS CONTAINING THE SAME, AND INTERMEDIATES THEREOF | Dainippon Pharmaceutical Co., Ltd. (JP) | 2000-09-20 | — | — | EP | disclosed |