⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL27626143 | 0.86 | — | — | |
| Imidazole SCHEMBL1952891 | 0.86 | ALDH1A1 (0.72) | — | |
| Imidazole SCHEMBL9151381 | 0.84 | ALDH1A1 (0.68) | — | |
| Imidazole SCHEMBL1702259 | 0.84 | — | — | |
| Imidazole SCHEMBL2333942 | 0.84 | — | — | |
| Imidazole SCHEMBL1827078 | 0.84 | ALDH1A1 (0.68) | — | |
| Imidazole SCHEMBL29241762 | 0.84 | ALDH1A1 (0.68) | — | |
| Imidazole SCHEMBL28165523 | 0.84 | — | — | |
| Imidazole SCHEMBL27493366 | 0.83 | — | — | |
| Pyrazine SCHEMBL1671928 | 0.83 | ALDH1A1 (0.87) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406400-A | Passivation fly ash filler for improving corrosion resistance and wear resistance of paint and preparation method thereof | 东北石油大学 | 2024-07-30 | — | — | CN | claimed |
| CN-112522836-A | Gauze fabric prepared from flame-retardant three-proofing fibers and preparation process thereof | 安徽和邦纺织科技有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| US-11492616-B2 | Method for modifying amino acid attenuator and use of same in production | INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2022-11-08 | — | — | US | disclosed |
| CN-112480893-B | Oil field desulfurization corrosion inhibitor and preparation method thereof | 中海油(天津)油田化工有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-113396161-A | Binding molecules to CD3 and uses thereof | 诺华股份有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-112522836-A | Gauze fabric prepared from flame-retardant three-proofing fibers and preparation process thereof | 安徽和邦纺织科技有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-112480893-A | Desulfurization corrosion inhibitor for oil field and preparation method thereof | 中海油(天津)油田化工有限公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-109689027-A | Triglycerides aural preparations and application thereof | 奥德纳米有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-107109419-A | Treatment of cancer using CD33 chimeric antigen receptor | 诺华股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106103485-A | Antibody molecules to PD-1 and uses thereof | 达纳-法伯癌症研究公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-103159788-A | Condensed imidazole formamide serving as transient receptor potential vanillin 3 (TRPV3) modifier | GLENMARK PHARMACEUTICALS SA | 2013-06-19 | — | — | CN | disclosed |
| US-6620882-B1 | Chemical intermediates for imidazoles, pyrazinones, and benzoidiazepinones; drug screening | ADVANCED SYNTECH, LLC | 2003-09-16 | — | — | US | disclosed |
| WO-2001083575-A1 | A NOVEL SOLID SUPPORT TEMPLATE FOR PREPARATION OF HIGHLY FUNCTIONALIZED HETEROCYCLE COMPOUNDS | ADVANCED SYNTECH, LLC A KENTUCKY LIMITED LIABILITY CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
| US-3968099-A | Process for the preparation of azo dyestuffs containing cyano groups | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |