Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112469 | 0.81 | — | — | |
| Trifluoroacetic Acid SCHEMBL8181430 | 0.78 | DPP8 (0.32) | CYP2C9FAAH | |
| Water SCHEMBL5127632 | 0.78 | LMNA (0.37) | — | |
| Water SCHEMBL7929821 | 0.78 | LMNA (0.37) | — | |
| Water SCHEMBL6763348 | 0.78 | LMNA (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL457553 | 0.74 | FAAH (0.36) | EPHX1FAAH | |
| Trifluoroacetic Acid SCHEMBL630048 | 0.74 | LMNA (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL60804 | 0.73 | FAAH (0.32) | FAAH | |
| Trifluoroacetic Acid SCHEMBL5494627 | 0.72 | FAAH (0.34) | EPHX1FAAH | |
| Trifluoroacetic Acid SCHEMBL28246387 | 0.71 | FAAH (0.31) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559179-B1 | Tinvention relates to the use of compounds as inhibitors of the fatty acid synthase FabH. | SMITHKLINE BEECHAM CORPORATION | 2003-05-06 | — | — | US | disclosed |
| EP-1206465-A4 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-1206465-A1 | FATTY ACID SYNTHASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014364-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-01 | — | — | WO | disclosed |