Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721174 | 1.00 | MEN1 (0.42) | MEN1KMT2AFAAHTP53CYP1A2 | |
| SCHEMBL13991599 | 0.97 | MEN1 (0.42) | MEN1KMT2AFAAHTP53CYP1A2 | |
| SCHEMBL14288365 | 0.97 | MEN1 (0.42) | MEN1KMT2AFAAHTP53CYP1A2 | |
| SCHEMBL14587249 | 0.97 | MEN1 (0.42) | MEN1KMT2AFAAHTP53CYP1A2 | |
| SCHEMBL718599 | 0.95 | MEN1 (0.39) | MEN1KMT2AFAAHTP53CYP1A2 | |
| SCHEMBL13679077 | 0.94 | MEN1 (0.40) | MEN1KMT2AFAAHTP53CYP1A2 | |
| SCHEMBL26835758 | 0.92 | KDM4E (0.46) | CYP3A4SOAT1LMNAALDH1A1ALOX15 | |
| SCHEMBL26858557 | 0.92 | KDM4E (0.46) | CYP3A4SOAT1LMNAALDH1A1ALOX15 | |
| SCHEMBL26835759 | 0.92 | KDM4E (0.46) | CYP3A4SOAT1LMNAALDH1A1ALOX15 | |
| SCHEMBL26835765 | 0.92 | KDM4E (0.46) | CYP3A4SOAT1LMNAALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604255-B1 | Novel reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER INC (US) | 2017-10-25 | — | — | EP | disclosed |
| US-8759499-B2 | Lipids for transfection of Eukaryotic cells | MOLECULAR TRANSFER, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| EP-2604255-A1 | Novel reagents for transfection of eukaryotic cells | Molecular Transfer, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2015780-B1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER INC (US) | 2012-12-12 | — | — | EP | disclosed |
| US-20120052574-A1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-7915230-B2 | Reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | MOLECULAR TRANSFER (US) | 2009-01-22 | — | — | US | disclosed |
| EP-2015780-A2 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | Molecular Transfer, Inc. (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007130073-A2 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | MOLECULAR TRANSFER, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023215-A1 | Novel reagents for transfection of eukaryotic cells | FUS, PHAX, PICALM | MEN1 1559/4885KMT2A 4019/4885FAAH 3351/4885 |
| US-20120052574-A1 | NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS | FUS, PHAX, PICALM | MEN1 1559/4885KMT2A 4019/4885FAAH 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.