SCHEMBL718599

SCHEMBL718599

CCCCCCCC/C=C\CCCCCCCCN(CC(O)CN)CC(O)C(O)CN(CCCCCCCC/C=C\CCCCCCCC)CC(O)CN

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
FAAH O00519 4/20 0.39
TP53 P04637 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP3A4 P08684 2/20 0.39
SOAT1 P35610 2/20 0.39
MAPT P10636 3/20 0.38
GMNN O75496 2/20 0.38
LMNA P02545 2/20 0.38
GLA P06280 2/20 0.38
POLB P06746 2/20 0.38
THRB P10828 2/20 0.38
CETP P11597 2/20 0.38
MAPK1 P28482 2/20 0.38
CXCR5 P32302 2/20 0.38
CCR6 P51684 2/20 0.38
BLM P54132 2/20 0.38
UBE2N P61088 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721173 0.95 MEN1 (0.42) MEN1KMT2AFAAHTP53CYP1A2
SCHEMBL721174 0.95 MEN1 (0.42) MEN1KMT2AFAAHTP53CYP1A2
SCHEMBL13679077 0.93 MEN1 (0.40) MEN1KMT2AFAAHTP53CYP1A2
SCHEMBL14587249 0.92 MEN1 (0.42) MEN1KMT2AFAAHTP53CYP1A2
SCHEMBL13991599 0.92 MEN1 (0.42) MEN1KMT2AFAAHTP53CYP1A2
SCHEMBL14288365 0.92 MEN1 (0.42) MEN1KMT2AFAAHTP53CYP1A2
SCHEMBL719201 0.91 HTT (0.43) TP53CYP1A2CYP3A4MAPTGMNN
SCHEMBL718257 0.91 HTT (0.43) TP53CYP1A2CYP3A4MAPTGMNN
SCHEMBL26835765 0.88 KDM4E (0.46) CYP3A4SOAT1LMNAALDH1A1ALOX15
SCHEMBL31285101 0.88 KDM4E (0.46) CYP3A4SOAT1LMNAALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025034802-A2 AGENTS FOR DELIVERY OF NUCLEIC ACIDS Life Technologies Corporation (US) 2025-02-13 WO claimed
WO-2025034764-A1 LIPIDS FOR DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS Life Technologies Corporation (US) 2025-02-13 WO claimed
CN-119137109-A Lipids for nucleic acid delivery 生命技术公司 2024-12-13 CN claimed
EP-4384508-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-06-19 EP claimed
EP-4175967-A2 TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF Life Technologies Corporation (US) 2023-05-10 EP claimed
CN-115803333-A Trinucleotide cap analogs, their preparation and use 生命技术公司 2023-03-14 CN claimed
WO-2023018990-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2023-02-16 WO claimed
WO-2022006368-A2 TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF Life Technologies Corporation (US) 2022-01-06 WO claimed
US-10968240-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2021-04-06 US claimed
US-10155780-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2018-12-18 US claimed
US-20170029448-A1 POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVEDDELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2017-02-02 US claimed
EP-2696678-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS Molecular Transfer, Inc. (US) 2014-02-19 EP claimed
WO-2013158127-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2013-10-24 WO claimed
EP-2015780-B1 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS MOLECULAR TRANSFER INC (US) 2012-12-12 EP claimed
WO-2012142622-A1 AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2012-10-18 WO claimed
US-7915230-B2 Reagents for transfection of eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2011-03-29 US claimed
US-20090023215-A1 Novel reagents for transfection of eukaryotic cells MOLECULAR TRANSFER (US) 2009-01-22 US claimed
EP-4710943-A2 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME Molecular Transfer, Inc. (US) 2026-03-18 EP disclosed
EP-2015780-A2 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS Molecular Transfer, Inc. (US) 2009-01-21 EP disclosed
WO-2007130073-A2 NOVEL REAGENTS FOR TRANSFECTION OF EUKARYOTIC CELLS MOLECULAR TRANSFER, INC. (US) 2007-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968240-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells PHOSPHO1, MBOAT7, PLTP MEN1 604/4885KMT2A 489/4885FAAH 3332/4885
US-10155780-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells PHOSPHO1, MBOAT7, PLTP MEN1 784/4885KMT2A 451/4885FAAH 3166/4885
US-20170029448-A1 POLYCATIONIC METHYL PHOSPHOLIPIDS FOR IMPROVEDDELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS PHOSPHO1, PLTP, MBOAT7 MEN1 700/4885KMT2A 518/4885FAAH 3226/4885
US-20090023215-A1 Novel reagents for transfection of eukaryotic cells FUS, PHAX, PICALM MEN1 1559/4885KMT2A 4019/4885FAAH 3351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.