Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.47 |
| ▸ | LONP1 | P36776 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6287638 | 0.96 | HDAC4 (0.47) | HDAC4MEF2DLONP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6288036 | 0.79 | HDAC4 (0.54) | HDAC4MEF2DNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25286304 | 0.79 | LONP1 (0.49) | LONP1NFKB1NFKB2RELAPSMB11 | |
| SCHEMBL25286303 | 0.79 | LONP1 (0.49) | LONP1NFKB1NFKB2RELAPSMB11 | |
| SCHEMBL29889201 | 0.79 | LONP1 (0.49) | LONP1NFKB1NFKB2RELAPSMB11 | |
| SCHEMBL9158908 | 0.76 | LONP1 (0.48) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL9158915 | 0.76 | LONP1 (0.48) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7211906 | 0.75 | ALDH1A1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL6286708 | 0.74 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| Hydrochloric Acid SCHEMBL6290917 | 0.73 | HDAC4 (0.44) | HDAC4MEF2DHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | HDAC4 4652/4885MEF2D 2563/4885LONP1 2671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.