Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 12/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.46 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.46 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.46 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.46 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.46 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.46 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.46 |
| ▸ | PSMB4 | P28070 | 5/20 | 0.46 |
| ▸ | PSMB6 | P28072 | 5/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.46 |
| ▸ | PSMB3 | P49720 | 5/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.46 |
| ▸ | PSMA6 | P60900 | 5/20 | 0.46 |
| ▸ | PSMA8 | Q8TAA3 | 5/20 | 0.46 |
| ▸ | PSMB7 | Q99436 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158915 | 1.00 | LONP1 (0.48) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL29889201 | 0.96 | LONP1 (0.49) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL25286303 | 0.96 | LONP1 (0.49) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL25286304 | 0.96 | LONP1 (0.49) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL2151194 | 0.83 | LONP1 (0.46) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL2151203 | 0.83 | LONP1 (0.46) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL9830710 | 0.82 | LONP1 (0.63) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL9830718 | 0.82 | LONP1 (0.63) | LONP1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL825451 | 0.82 | CTSK (0.64) | FOLH1CTSK | |
| SCHEMBL4404268 | 0.82 | CTSK (0.64) | FOLH1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377665-B1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE | UNIV TEXAS (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0536203-B1 | COMBINED TREATMENT WITH GnRH ANTAGONIST AND GnRH TO CONTROL GONADOTROPIN LEVELS IN MAMMALS | APPLIED RESEARCH SYSTEMS (AN) | 1995-02-08 | — | — | EP | disclosed |
| WO-1991019743-A2 | COMBINED TREATMENT WITH GnRH ANTAGONIST AND GnRH TO CONTROL GONADOTROPIN LEVELS IN MAMMALS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1991-12-26 | — | — | WO | disclosed |
| EP-0377665-A1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE. | UNIV TEXAS (US) | 1990-07-18 | — | — | EP | disclosed |
| WO-1989009786-A1 | PEPTIDE DERIVATIVES | SANDOZ AG (CH) | 1989-10-19 | — | — | WO | disclosed |
| WO-1989001944-A1 | EFFECTIVE ANTAGONISTS OF THE LUTEINIZING HORMONE RELEASING HORMONE WHICH RELEASE NEGLIGIBLE HISTAMINE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1989-03-09 | — | — | WO | disclosed |