Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268494 | 0.89 | CNR2 (0.55) | PLA2G2A | |
| SCHEMBL9268582 | 0.89 | PLA2G2A (0.53) | PLA2G2A | |
| SCHEMBL7207563 | 0.88 | PLA2G2A (0.66) | PLA2G2A | |
| SCHEMBL7207533 | 0.87 | PLA2G2A (0.55) | PLA2G2A | |
| SCHEMBL9269673 | 0.87 | CNR2 (0.53) | PLA2G2A | |
| SCHEMBL9273557 | 0.87 | PLA2G2A (0.52) | PLA2G2A | |
| SCHEMBL9266169 | 0.87 | CNR2 (0.53) | PLA2G2A | |
| SCHEMBL9270156 | 0.86 | PLA2G2A (0.48) | PLA2G2A | |
| SCHEMBL7212268 | 0.84 | PLA2G2A (0.57) | PLA2G2A | |
| SCHEMBL7211881 | 0.84 | PSEN1 (0.54) | PLA2G2APSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923546-B1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2003-11-26 | — | — | EP | claimed |
| EP-0923546-A1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | Merckle GmbH (DE) | 1999-06-23 | — | — | EP | claimed |
| WO-1998005637-A1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A¿2? | MERCKLE GMBH (DE) | 1998-02-12 | — | — | WO | claimed |
| EP-0923546-B1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2003-11-26 | — | — | EP | disclosed |