Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268492 | 0.89 | PLA2G2A (0.64) | PLA2G2A | |
| SCHEMBL9268578 | 0.88 | PLA2G2A (0.69) | PLA2G2A | |
| SCHEMBL7211985 | 0.88 | PLA2G2A (0.53) | PLA2G2A | |
| SCHEMBL7207531 | 0.86 | PLA2G2A (0.70) | PLA2G2A | |
| SCHEMBL9269666 | 0.86 | PLA2G2A (0.67) | PLA2G2A | |
| SCHEMBL9273553 | 0.86 | PLA2G2A (0.67) | PLA2G2A | |
| SCHEMBL9266165 | 0.86 | PLA2G2A (0.67) | PLA2G2A | |
| SCHEMBL9270154 | 0.84 | PLA2G2A (0.62) | PLA2G2A | |
| SCHEMBL7955147 | 0.83 | PLA2G2A (0.55) | PLA2G2A | |
| SCHEMBL3680966 | 0.83 | PLA2G2A (0.75) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923546-B1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2003-11-26 | — | — | EP | claimed |
| US-6310217-B1 | ANTIINFLAMMATORY AND ANALGESIC AGENTS | MERCKLE GMBH (DE) | 2001-10-30 | — | — | US | claimed |
| EP-0923546-B1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-6310217-B1 | ANTIINFLAMMATORY AND ANALGESIC AGENTS | MERCKLE GMBH (DE) | 2001-10-30 | — | — | US | disclosed |