Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928387 | 0.86 | ESR1 (0.59) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL22631904 | 0.77 | ESR1 (0.52) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL25273609 | 0.77 | ESR1 (0.52) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL15371224 | 0.72 | ESR1 (0.62) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL7212060 | 0.72 | ESR1 (0.62) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL19401505 | 0.72 | ESR1 (0.64) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL18002678 | 0.72 | ESR1 (0.62) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL237273 | 0.69 | LMNA (0.67) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL8952160 | 0.69 | ESR1 (0.52) | ESR1ESR2CYP3A4HSD17B10LMNA | |
| SCHEMBL10458795 | 0.69 | ESR1 (0.44) | ESR1ESR2CYP3A4HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272565-A2 | FLAME-RETARDANT RESIN MOLDING | GENERAL ELECTRIC COMPANY (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001072905-A2 | FLAME-RETARDANT RESIN MOLDING | GENERAL ELECTRIC COMPANY (US) | 2001-10-04 | — | — | WO | disclosed |