Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19401505 | 0.89 | ESR1 (0.64) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL5907707 | 0.82 | KIF11 (0.67) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL6007959 | 0.82 | KIF11 (0.67) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL1171482 | 0.80 | ESR1 (0.56) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL8661272 | 0.78 | ALOX15 (0.56) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL9296155 | 0.78 | KIF11 (0.45) | KIF11CYP3A4HPGDTSHRAPP | |
| SCHEMBL13149650 | 0.77 | LMNA (0.52) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL3097103 | 0.77 | LMNA (0.52) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL10715675 | 0.75 | ALOX15 (0.61) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL27309628 | 0.75 | ALOX15 (0.61) | ESR1ESR2CYP3A4LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498803-A | SOLVENT RESISTANT POLYETHERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1996-03-12 | — | — | US | disclosed |