Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213267 | 0.85 | LSS (0.34) | LSS | |
| SCHEMBL7218367 | 0.85 | LSS (0.46) | LSS | |
| SCHEMBL7218490 | 0.82 | LSS (0.40) | LSS | |
| SCHEMBL7217117 | 0.79 | LSS (0.58) | LSS | |
| SCHEMBL7212194 | 0.78 | LSS (0.52) | LSS | |
| SCHEMBL7218350 | 0.75 | LSS (0.43) | LSS | |
| SCHEMBL5637928 | 0.73 | LSS (0.48) | LSS | |
| SCHEMBL6992807 | 0.73 | LSS (0.46) | LSS | |
| SCHEMBL3367439 | 0.72 | LSS (0.59) | LSS | |
| SCHEMBL7212207 | 0.72 | THRA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358162-A1 | DIHYDROINDOLE AND TETRAHYDROQUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002050041-A1 | DIHYDROINDOLE AND TETRAHYDROQUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-27 | — | — | WO | disclosed |