Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960362 | 0.95 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2HSD17B10PKM | |
| SCHEMBL29263667 | 0.94 | RAB9A (0.55) | RAB9AMAPTSMN1; SMN2HSD17B10PKM | |
| SCHEMBL8616882 | 0.82 | MEN1 (0.56) | RAB9AMAPTSMN1; SMN2HSD17B10PKM | |
| SCHEMBL8619440 | 0.78 | RAB9A (0.77) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10956675 | 0.78 | TDP1 (0.61) | RAB9AMAPTSMN1; SMN2HSD17B10PKM | |
| SCHEMBL34464350 | 0.77 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL21997883 | 0.77 | RAB9A (0.54) | RAB9AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL8616051 | 0.77 | KDM4E (0.50) | HTR1ACYP2D6CYP2C19KDM4ECYP2C9 | |
| Hydrochloric Acid SCHEMBL8618560 | 0.77 | RAB9A (0.74) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7299163 | 0.77 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2HSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-0922050-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997042205-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | disclosed |