Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263667 | 0.98 | RAB9A (0.55) | RAB9AMAPTSMN1; SMN2HSD17B10HTR1A | |
| SCHEMBL7212283 | 0.95 | RAB9A (0.62) | RAB9AMAPTSMN1; SMN2HSD17B10HTR1A | |
| SCHEMBL8616882 | 0.81 | MEN1 (0.56) | RAB9AMAPTSMN1; SMN2HSD17B10HTR1A | |
| SCHEMBL8616243 | 0.79 | RAB9A (0.69) | RAB9AMAPTSMN1; SMN2HTR1AKMT2A | |
| SCHEMBL10337042 | 0.79 | MAPT (0.64) | RAB9AMAPTSMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL8619127 | 0.78 | DRD3 (0.51) | HTR1AKDM4E | |
| SCHEMBL6790333 | 0.78 | TDP1 (0.71) | RAB9AMAPTSMN1; SMN2CYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL8617348 | 0.78 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2HTR1AKMT2A | |
| SCHEMBL1999435 | 0.78 | RAB9A (0.90) | RAB9AMAPTSMN1; SMN2PKMCYP1A2 | |
| SCHEMBL11996369 | 0.76 | RAB9A (0.87) | RAB9AMAPTSMN1; SMN2PKMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491374-B1 | Bisphosphonic acid derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5280022-A | Containing an amine group | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | disclosed |
| EP-0491374-A1 | Bisphosphonic acid derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-24 | — | — | EP | disclosed |