Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | CALCRL | Q16602 | 17/20 | 0.43 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252895 | 0.72 | KCNH2 (0.47) | KCNH2CALCRLRAMP1 | |
| SCHEMBL7744132 | 0.72 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL7744591 | 0.72 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3247608 | 0.72 | KCNH2 (0.57) | KCNH2CALCRLRAMP1 | |
| SCHEMBL8462992 | 0.72 | KCNH2 (0.82) | KCNH2CALCRLRAMP1 | |
| SCHEMBL3859605 | 0.70 | GABRP (0.61) | KCNH2CALCRLRAMP1 | |
| SCHEMBL1834474 | 0.70 | GABRP (0.61) | KCNH2CALCRLRAMP1 | |
| SCHEMBL8223082 | 0.68 | KCNH2 (0.73) | KCNH2CALCRLRAMP1 | |
| L-768673 SCHEMBL7207125 | 0.67 | KCNH2 (1.00) | KCNH2CALCRLRAMP1 | |
| SCHEMBL8462904 | 0.67 | KCNH2 (0.77) | KCNH2CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907644-A4 | PHARMACEUTICAL PREPARATION | MERCK & CO INC (US) | 2003-02-05 | — | — | EP | disclosed |
| EP-0907644-A1 | PHARMACEUTICAL PREPARATION | Merck & Co., Inc. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998000405-A1 | PHARMACEUTICAL PREPARATION | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |