Methacrylic Acid

Methacrylic Acid

SCHEMBL7212839

C=C(C)C(=O)O.C=C(C)C(=O)O.CCCOCCC.OCCCCC(O)CO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.39
USP2 O75604 2/20 0.38
GPR84 Q9NQS5 4/20 0.36
FFAR4 Q5NUL3 1/20 0.35
FFAR1 O14842 1/20 0.35
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
PSMD14 O00487 2/20 0.32
PLA2G1B P04054 2/20 0.32
MMP2 P08253 2/20 0.32
ATG4B Q9Y4P1 2/20 0.32
HSP90AA1 P07900 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
RAD52 P43351 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 2/20 0.32
ACACB O00763 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL7213129 0.89 THRB (0.42) PLA2G2CUSP2KDM4EALDH1A1ALOX15
Methacrylic Acid SCHEMBL8923925 0.87 THRB (0.39) PLA2G2CUSP2GPR84FFAR4FFAR1
Methacrylic Acid SCHEMBL7218292 0.86 USP2 (0.42) PLA2G2CUSP2KDM4EALDH1A1ALOX15
Methacrylic Acid SCHEMBL7213133 0.86 USP2 (0.42) PLA2G2CUSP2KDM4EALDH1A1ALOX15
Methacrylic Acid SCHEMBL7212837 0.86 TSHR (0.40) ALDH1A1MEN1KMT2ALMNATSHR
Acrylic Acid SCHEMBL7214460 0.85 USP2 (0.38) PLA2G2CUSP2GPR84FFAR4FFAR1
Methacrylic Acid SCHEMBL7218280 0.84 TSHR (0.43) ALDH1A1MEN1KMT2ALMNATSHR
Methacrylic Acid SCHEMBL7212810 0.84 TSHR (0.43) ALDH1A1MEN1KMT2ALMNATSHR
Methacrylic Acid SCHEMBL7219058 0.84 TSHR (0.43) ALDH1A1MEN1KMT2ALMNATSHR
Methacrylic Acid SCHEMBL7219056 0.84 TSHR (0.43) ALDH1A1MEN1KMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6624236-B1 Sol-gel-condensable cyclosiloxane(meth) acrylates; dentistry 3M ESPE AG (DE) 2003-09-23 US disclosed