Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL7213133 | 0.90 | USP2 (0.42) | THRBPLA2G2CUSP2KDM4EALDH1A1 | |
| Methacrylic Acid SCHEMBL7218292 | 0.90 | USP2 (0.42) | THRBPLA2G2CUSP2KDM4EALDH1A1 | |
| Methacrylic Acid SCHEMBL7212839 | 0.89 | PLA2G2C (0.39) | PLA2G2CUSP2KDM4EALDH1A1ALOX15 | |
| Methacrylic Acid SCHEMBL7916650 | 0.86 | THRB (0.56) | THRBPLA2G2CALDH1A1LMNATGFBR1 | |
| Methacrylic Acid SCHEMBL6760926 | 0.86 | THRB (0.56) | THRBPLA2G2CALDH1A1LMNATGFBR1 | |
| Methacrylic Acid SCHEMBL15409 | 0.86 | THRB (0.56) | THRBPLA2G2CALDH1A1LMNATGFBR1 | |
| Methacrylic Acid SCHEMBL7214459 | 0.85 | HSD17B10 (0.41) | THRBUSP2KDM4EALDH1A1ALOX15 | |
| Methacrylic Acid SCHEMBL11210689 | 0.85 | USP2 (0.53) | THRBPLA2G2CUSP2KDM4EALDH1A1 | |
| Acrylic Acid SCHEMBL7212826 | 0.84 | THRB (0.42) | THRBPLA2G2CUSP2KDM4EALDH1A1 | |
| Methacrylic Acid SCHEMBL7219389 | 0.83 | HSD17B10 (0.45) | THRBPLA2G2CUSP2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624236-B1 | Sol-gel-condensable cyclosiloxane(meth) acrylates; dentistry | 3M ESPE AG (DE) | 2003-09-23 | — | — | US | disclosed |
| EP-1141094-B1 | CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS | 3M ESPE AG (DE) | 2002-07-24 | — | — | EP | disclosed |