Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208533 | 1.00 | CYP2C19 (0.39) | CYP2C19HIF1AKCNN4SMN1; SMN2NR1H2 | |
| SCHEMBL7772741 | 0.72 | TSHR (0.36) | CYP2C19HIF1APTPN1KMT2A | |
| SCHEMBL7207839 | 0.64 | KCNN4 (0.38) | CYP2C19HIF1AKCNN4SMN1; SMN2POLB | |
| SCHEMBL10982127 | 0.62 | KCNN4 (0.58) | CYP2C19HIF1AKCNN4NR1H2NR1H3 | |
| SCHEMBL4012323 | 0.62 | KCNN4 (0.58) | CYP2C19HIF1AKCNN4NR1H2NR1H3 | |
| SCHEMBL6387363 | 0.62 | CYP2C19 (0.53) | CYP2C19HIF1AKCNN4SMN1; SMN2POLB | |
| SCHEMBL7212918 | 0.61 | ALDH1A1 (0.35) | CYP2C19SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL1081533 | 0.61 | HIF1A (0.57) | CYP2C19HIF1AKCNN4SMN1; SMN2KMT2A | |
| SCHEMBL1051513 | 0.61 | CYP2C19 (0.57) | CYP2C19HIF1AKCNN4SMN1; SMN2POLB | |
| SCHEMBL3363877 | 0.61 | CYP2C19 (0.57) | CYP2C19HIF1AKCNN4SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |